Newly discovered activity of the leukemia drug, nilotinib, shows promise for being useful to treat certain types of cancer. Hedgehog-dependent medulloblastoma is a deadly brain cancer that makes up about one-third of all childhood brain cancers. The Hedgehog (Hh) molecular signaling pathway and its specific component, Smoothened (SMO), is important for normal embryonic development. Abnormal […]

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