Since the discovery of cystic fibrosis (CF) in 1938, there have been significant increases in life expectancy for those with CF. Treatments such as antibiotics and physical therapy are responsible for the increased life expectancy into a person’s 30s.4  However, these treatments still have limits as they do not directly target the problem behind CF […]

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Cystic fibrosis (CF) is a genetic disorder, caused by mutations in the cystic fibrosis transmembrane conductance regulator protein. Clinically, CF contributes to the dysfunction of multiple organs and negatively affects the airway, which makes breathing difficult. Patients with CF are also at a higher risk of infections and malnutrition. In 2015, the Food and Drug […]

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A recent phase III clinical trial reports positive findings for a three-drug combination treatment for cystic fibrosis. Cystic fibrosis (CF) is a chronic and often fatal genetic disease that affects nearly 80,000 adults and children worldwide. Typically, CF affects the respiratory and digestive system, as well as the sweat glands and reproductive system. Although there […]

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Researchers in Chicago, USA investigated whether blood can be used to identify specific problems that need to be targeted in cystic fibrosis treatment. Cystic fibrosis is a disease that primarily affects the lungs and digestive system. People with cystic fibrosis experience breathing problems, frequent lung infections, gradual deterioration of the lungs. Some patients also experience […]

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A triple drug combination for treating the underlying cause of cystic fibrosis is currently under study. The preliminary results show a significant improvement in lung function. Cystic fibrosis is a genetic disease affecting the chloride channels in the body. These chloride channels are called cystic fibrosis transmembrane conductance regulator (CFTR). The major body systems affected […]

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A recent literature review published in The Lancet Oncology analyzed the probability of gastrointestinal cancer risk in cystic fibrosis patients. Cystic fibrosis is a genetic disease. It is caused by a change in the gene that forms a protein in the cell membranes called cystic fibrosis transmembrane conductance regulator (CFTR). The defective protein that is […]

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